PF4 anticorps

N° du produit ABIN5026898

Cet anticorps Poulet Polyclonal détecte spécifiquement PF4 dans WB, IHC, ELISA et AGG. Il présente une réactivité envers Mammifères.

Aperçu rapide pour PF4 anticorps (ABIN5026898)

Antigène: PF4 (Platelet Factor 4 (PF4))

Reactivité: Mammifères

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp PF4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Agglutination (AGG)

Détail du produit anti-PF4 anticorps

Attributs du produit: IgY-antibody

Purification: Precipitation with ammoniumsulfate , dialyse and fitration

Immunogène: raw, native protein

Isotype: IgY

Information d'application

Indications d'application: Perform a chessboard titation before the first application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Détails sur PF4

Antigène: PF4 (Platelet Factor 4 (PF4))

Autre désignation: Platelet-factor 4

Sujet: Platelet-Factor 4 (PF4) complex is the antigen in heparin-induced thrombocytopenia (HIT), an idiosyncratic autoimmune reaction to the administration of the anticoagulant heparin. Its autoantibodies have also been found in patients with thrombosis with similar HIT although they have received no prior administration of heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. It is usually found in a complex with proteoglycan.